Monday, August 7, 2017

What are the early symptoms of nephrotic syndrome?



Nephrotic syndrome main symptoms: a large number of proteinuria, hypoproteinemia, hyperlipidemia, high blood pressure

(A) proteinuria normal daily urinary protein excretion of not more than 150mg. A large number of proteinuria is due to abnormal glomerular filtration membrane caused by normal glomerular filtration membrane on the selective filtration of plasma protein, Can effectively prevent the vast majority of plasma protein from glomerular filtration, only a very small amount of plasma protein into the glomerular filtrate.

(B) hypoalbuminemia Low albuminemia seen in most patients with nephrotic syndrome, that is, serum albumin levels below 30g / L. The main reason is the loss of albumin in urine, but the two are not completely parallel, Because plasma albumin values ​​are the result of albumin synthesis and catabolic balance.

(C) the presence and severity of edema and edema is positively correlated with the degree of hypoproteinemia, but the exception is not uncommon.

(Ch) and low-density lipoprotein cholesterol (LDL-Ch) were significantly increased, and the contents of total cholesterol (LDL-Ch) were significantly higher than those of the control group (P <0.05) Triglyceride (TG) and very low density lipoprotein cholesterol (VLDL-Ch) increased.

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