Monday, July 24, 2017

Early Detection of Renal Damage in Hypertension and Traditional Chinese Medicine

Overview: Hypertension is an important risk factor for increased renal function changes, is one of the important target organs of hypertension-related damage, 25% of end-stage renal disease and hypertension. Clinically caused by changes in renal structure and function of hypertension, known as hypertensive kidney damage. Good blood pressure control is undoubtedly the basis for the suppression of hypertensive kidney damage, but in recent years despite the widespread use of hypertension drugs, hypertension caused by end-stage renal disease (ESRD) incidence rate is on the rise. Over the past 10 years, the incidence of ESRD in the United States at an annual rate of 9% growth, which caused by high blood pressure caused by ESRD new patients accounted for 28%, which prompted the clinical application of antihypertensive drug therapy to protect the role of renal function It is not enough
Hypertension: blood pressure is the main feature of a class of diseases in general, including the primary hypertension and secondary hypertension. The diagnostic criteria are:
Hypertension: systolic blood pressure ≥ 140 mm Hg, diastolic blood pressure ≥ 90 mm Hg, two can be diagnosed in line with one.
Prehypertension: systolic blood pressure ≥ 120 mm Hg but <140 mm Hg, diastolic blood pressure ≥ 80 mm Hg but <90 mm Hg, two can meet the diagnosis of prehypertension, also known as normal high Value of blood pressure.
Ideal blood pressure: systolic blood pressure <120 mm Hg, and diastolic blood pressure <80 mm Hg.
Essential Hypertension: refers to the reasons for elevated blood pressure can not be explained that the disease can be explained, that is, after a doctor diagnosed, ruled out that can cause high blood pressure caused by the disease, known as primary hypertension, also known as High blood pressure.
Hypertensive renal damage: refers to the increase in blood pressure caused by decreased renal function and structural changes. Mainly for renal tubular concentration - dilution abnormalities, glomerular filtration function abnormalities, cortical thinning, renal atrophy. Outcome - uremia.
Early renal damage performance: nocturia increased, normal urine test, renal function (creatinine, urea nitrogen normal, normal or slightly elevated uric acid) normal. Random urine microalbumin positive, urinary albumin, urinary α1-microglobulin, transferrin, immunoglobulin G increased.
Early diagnosis of renal damage criteria: urine, blood urea nitrogen (BUN), creatinine (SCr) normal; 24h urinary protein 30 ~ 300mg, albumin / creatinine male ≥ 2.5, female ≥3.1, in line with the above criteria to determine early renal damage The
The results of normal or less than the above indicators as no kidney damage.
Urinary α1-microglobulin (α-1 MG molecular weight): Renal tubule proximal tubule injury marker protein.
Transferrin (TRF): negatively charged, is the marker protein of glomerular filtration membrane charge selective barrier damage.
Urinary microalbumin (MA): Glomerular filtration membrane charge selective barrier damage marker protein, renal tubular reabsorption is also one of the signs of damage.
Immunoglobulin G (IgG): IgG is the most abundant and most important immunoglobulin in serum and is a marker protein for selection of barrier damage in glomerular filtration membrane screens.
Early detection measures:
Tip symptoms: nocturia increased, there are bubbles in the urine.
Regular check: renal function (creatinine, urea, uric acid), urinary protein detection (four or five)
Precautionary approach:
Regularly check the above indicators, found abnormal early treatment.
Control blood pressure, generally below 135/85 mm Hg
Choose the right control of blood pressure drugs (Chinese and Western medicine).
Tea, medicated.
To avoid the role of kidney damage in Chinese and Western medicine.
Knowledge of Chinese medicine
Through a large number of clinical cases, and analysis of TCM syndromes, the current view that the pathogenesis of renal damage in hypertension is liver and kidney, or both blood stasis, or both phlegm, once there will often be The pathogenesis of kidney deficiency is involved. Can be used to Yin, kidney, blood and other methods of treatment
Case 1: (slightly)
Case 2: (slightly)
On the protection of kidney damage or therapeutic effect of traditional Chinese medicine:
Liu Wei Di Huang Wan: habitat, yam, dogwood, Poria, Alisma, Dan.
Single herb: Astragalus, corn must, raw hawthorn, Shouwu, Salvia and so on. You can add cooking food, on behalf of the tea.
Tips: the specific treatment of medication, please use the doctor prescribed pulse, not self-medication use.

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